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The Microbial Ecophysiology Lab focuses on understanding the regulation of cellular processes in methane-producing microbes from the Domain Archaea (methanogens or methanogenic archaea) and their role in free-living environments and host-associated microbiomes. Why? Because currently archaea diversity is analyzed principally at the (meta)-genomic level, providing valuable information on their metabolic and ecological potential; however, a comprehensive understanding of their physiology and regulation is necessary.

Our fantastic team uses omics analysis combined with detailed functional characterization of proteins, cofactors, and metabolites to further our understanding of the regulation of cellular processes and ultrastructure in archaea, as well as their ability to interact with other organisms and survive under stress conditions.

Through this comprehensive approach, our team works on topics with ecological, biomedical, biotechnological and astrobiological applications (e.g., production of unusual proteins and metabolites, drug resistance and detoxification, and mitigation of global warming through carbon sequestration), as well as strategies of microbial isolation, Metabolic Pathway Engineering, Metabolic Modeling and Protein Directed Evolution.

Have you noticed that some labs generate a lot of waste that is not recyclable? Our goal is to run an eco-friendly lab, where all members use strategies to reduce waste, reuse materials and limit the use of plastics, dyes and non-recyclable material (when possible). This strategy will help us reduce costs and have less negative impact on the environment.

Interested in joining the lab or collaborating with us? Please contact us!

We do NOT have direct admission to our graduate programs. All prospective students must apply by following this admissions process.

Read and cite our research! See our manuscripts on Google Scholar and ResearchGate. 

The fantastic Microbial Ecophysiology Lab

Logo for Microbial Ecophysiology Lab

We are people who do scientific research, and we actively work to include diverse perspectives in our team.

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Connect With Us

Upcoming MCB Events

  1. Nov 14 GO:MCB November Coffee Hour 9:00am
  2. Nov 14 MCB Cell and Developmental Biology Journal Club 12:30pm
  3. Nov 15 MCB Research in Progress: Garrett Skidds 12:20pm
  4. Nov 15 MCB Dissertation Defense: Gabrielle E. Corso 3:00pm
  5. Nov 18 MCB Micro Journal Club 4:00pm
All Events »

Contact

Phone: (860) 486-8960
geo_santiagom@uconn.edu
Address: 91 N. Eagleville Rd
Unit 3125
Storrs, CT 06269-3125
More: Office: TLS 286