The Microbial Ecophysiology Lab focuses on understanding the regulation of cellular processes in methane-producing microbes from the Domain Archaea (methanogens or methanogenic archaea) and their role in free-living environments and host-associated microbiomes. Why? Because currently archaea diversity is analyzed principally at the (meta)-genomic level, providing valuable information on their metabolic and ecological potential; however, a comprehensive understanding of their physiology and regulation is necessary.
Our fantastic team uses omics analysis combined with detailed functional characterization of proteins, cofactors, and metabolites to further our understanding of the regulation of cellular processes and ultrastructure in archaea, as well as their ability to interact with other organisms and survive under stress conditions.
Through this comprehensive approach, our team works on topics with ecological, biomedical, biotechnological and astrobiological applications (e.g., production of unusual proteins and metabolites, drug resistance and detoxification, and mitigation of global warming through carbon sequestration), as well as strategies of microbial isolation, Metabolic Pathway Engineering, Metabolic Modeling and Protein Directed Evolution.
Have you noticed that some labs generate a lot of waste that is not recyclable? Our goal is to run an eco-friendly lab, where all members use strategies to reduce waste, reuse materials and limit the use of plastics, dyes and non-recyclable material (when possible). This strategy will help us reduce costs and have less negative impact on the environment.
Interested in joining the lab or collaborating with us? Please contact us!
We do NOT have direct admission to our graduate programs. All prospective students must apply by following this admissions process.
Read and cite our research! See our manuscripts on Google Scholar and ResearchGate.
The fantastic Microbial Ecophysiology Lab
We are people who do scientific research, and we actively work to include diverse perspectives in our team.
Upcoming MCB Events
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Oct
17
MCB Cell and Developmental Journal Club 12:30pm
MCB Cell and Developmental Journal Club
Thursday, October 17th, 2024
12:30 PM - 01:30 PM
TLS 263
This week in Cell and Developmental Biology Journal Club, Claire Peterson will lead a discussion of “Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response” by Lopez-Domenech et al., 2021.
Contact Information:
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Oct
18
MCB Research in Progress: Derrick Kamp and Katie Kyle 12:20pm
MCB Research in Progress: Derrick Kamp and Katie Kyle
Friday, October 18th, 2024
12:20 PM
BPB 130
Derrick Kamp
Nyholm Lab
Sweet Structuring: Glycan and bacterial taxa associations in a symbiotic organ of the Hawaiian bobtail squidKatie Kyle
Klassen LabUntrimmed ITS2 metabarcode sequences cause artificially reduced abundances of specific fungal taxa.
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Oct
22
MCB Seminar Series: Abhijit Deb Roy 3:30pm
MCB Seminar Series: Abhijit Deb Roy
Tuesday, October 22nd, 2024
03:30 PM
BPB 131
Abhijit Deb Roy
Assistant Professor, UConn HealthHost: Barbara Mellone
Deciphering the tubulin code of mechanobiology
We have applied cell biology and synthetic biology approaches to establish a causal relationship between microtubule post-translational modifications and actomyosin contractility in migrating cells.
Bio:
Dr. Deb Roy obtained his PhD in Biomedical Sciences from UConn Health, where he studied molecular interactions between bone cells. He did his post-doctoral fellowship at Johns Hopkins Medical Institute on the crosstalk between actin and microtubules. His lab at UConn Health investigates cytoskeletal dynamics and cell motility.Contact Information:
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Oct
25
NESS 24 - North East Structure Symposium All Day
NESS 24 - North East Structure Symposium
Friday, October 25th, 2024
All Day
Grossman Auditorium in the UConn Health Cell Sciences Building, 400 Farmington Ave., Farmington CT.
NMR and cryo-EM: A ConversationConfirmed speakers include Harald Schwalbe (U Frankfurt), Wolfgang Peti (UCH), Elizabeth Wright (UW-Madison), Wah Chiu (Stanford), Rui Zhang (Wash U), Paul Robustelli (Dartmouth), Jean Baum (Rutgers) and Andy Byrd (UCH).
This year, in addition to a poster session (with prizes), a number of poster presenters will be invited to give short promoted talks.The day-long meeting is free, including breakfast and lunch, however we do ask that you register at https://forms.office.com/r/RUUg1sXVhcContact Information:
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Oct
25
MCB Research in Progress: Nadine Lebek 12:20pm
MCB Research in Progress: Nadine Lebek
Friday, October 25th, 2024
12:20 PM
BPB 130
Nadine Lebek
Campellone LabContact Information:
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Contact
Phone: | (860) 486-8960 |
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E-mail: | geo_santiagom@uconn.edu |
Address: | 91 N. Eagleville Rd Unit 3125 Storrs, CT 06269-3125 |
More: | Office: TLS 286 |