The Microbial Ecophysiology Lab focuses on understanding the regulation of cellular processes in methane-producing microbes from the Domain Archaea (methanogens or methanogenic archaea) and their role in the health of ecosystems and host-associated microbiomes. Why? Because currently archaea diversity is analyzed principally at the (meta)-genomic level, providing valuable information on their metabolic and ecological potential; however, a comprehensive understanding of their physiology and molecular mechanisms will help us understand the unique biology of archaea.
Our fantastic team uses omics analysis combined with detailed functional characterization of proteins, cofactors, and metabolites to further our understanding of the regulation of cellular processes and ultrastructure in archaea, as well as their ability to interact with other organisms and survive under stress conditions.
Through this comprehensive approach, our team works on topics with ecological, biomedical, biotechnological and astrobiological applications (e.g., production of unusual proteins and metabolites, drug resistance and detoxification, and mitigation of global warming through carbon sequestration), as well as strategies of microbial isolation, Metabolic Pathway Engineering, Metabolic Modeling and Protein Directed Evolution.
Have you noticed that some labs generate a lot of waste that is not recyclable? Our goal is to run an eco-friendly lab, where all members use strategies to reduce waste, reuse materials and limit the use of plastics, dyes and non-recyclable material (when possible). This strategy will help us reduce costs and have less negative impact on the environment.
Interested in joining the lab or collaborating with us? Please contact us!
We do NOT have direct admission to our graduate programs. All prospective students must apply by following this admissions process.
Read and cite our research! See our manuscripts on Google Scholar and ResearchGate.
The fantastic Microbial Ecophysiology Lab
We are people who do scientific research, and we actively work to include diverse perspectives in our team.
Upcoming MCB Events
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Jan
31
MCB Research in Progress 12:20pm
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Feb
4
MCB Seminar Series: Dr. Nahui Medina-Chavez 3:30pm
MCB Seminar Series: Dr. Nahui Medina-Chavez
Tuesday, February 4th, 2025
03:30 PM - 04:30 PM
BPB 130
Dr. Nahui Medina-Chavez
Postdoctoral Associate
University of Minnesota
Host: Geo Santiago-MartinezProbing the Last Frontier: From Archaea cultivation to the long term experiment in halophiles
Summary: Dr. Medina-Chavez will cover the great need of archaeal experimentation, covering cultivation challenges to my most recentexperimental design to experimentally investigate adaptive responses in halophiles. In these set of experiments, I continuously transfer two strains (Halobacterium salinarum and Salinibacter ruber) in a multidimensional resourcecomponent and salt saturated conditions in poor and rich environments.
Bio: Dr. Medina-Chavez is a microbiologist and a postdoctoral researcher at the University of Minnesota. Her research focuses on evolutionary biology, microbial genomics, and the physiology of archaea. With over eight years of dedication and stewardship, she has cultivated an extensive halophilic archaeal collection. Through genomics and experimental evolution, Medina-Chavez studies the adaptive mechanisms of haloarchaea, showcasing theirplastic metabolic processes, providing valuable insights into microbial responses to environmental change, andexploring dual adaptability and its trade-offs.
Learn more about Dr. Medina-Chavez’s work
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2021.693193/full
https://pubmed.ncbi.nlm.nih.gov/37279013/
https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2023.1276438/full
https://scholar.google.com/citations?user=LkFZPrYAAAAJ&hl=en
Contact Information:
More -
Feb
6
MCB Grad Recruitment All Day
MCB Grad Recruitment
Thursday, February 6th, 2025
All Day
Biology/Physics Building
MCB Graduate Student Recruitment
This event is by invitation only.
Contact Information:
More -
Feb
7
MCB Grad Recruitment All Day
MCB Grad Recruitment
Friday, February 7th, 2025
All Day
Biology/Physics Building
MCB Graduate Student Recruitment
This event is by invitation only.
Contact Information:
More -
Feb
7
MCB Research in Progress 12:20pm
Contact
Phone: | (860) 486-8960 |
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E-mail: | geo_santiagom@uconn.edu |
Address: | 91 N. Eagleville Rd Unit 3125 Storrs, CT 06269-3125 |
More: | Office: TLS 286 |